Complex Synthetics

The development of synthetic molecules for use in drug substances, medical devices and diagnostic agents is becoming increasingly complex. The number of steps required to synthesize certain molecules has increased considerably, and so has the need for enabling technologies to overcome bioavailability challenges. These complex molecules require a step change in advanced process, analytical and manufacturing technologies and expertise.

Snapdragon Chemistry, now a part of Cambrex, can help you develop and cGMP manufacture complex synthetics. Our chemists use data-rich experimentation and advanced process analytical technology (PAT) tools, enabled by proprietary LabOS™ software, to efficiently determine the design space and optimal conditions for manufacturing complex synthetics. We leverage technologies such as solid-phase synthesis, tangential flow filtration, nanofiltration, ion exchange chromatography and wiped film evaporation to enable robust and reproducible cGMP manufacture of complex synthetics, such as:

  • Block copolymers
  • Polymeric linkers
  • Functionalized dendrimers
  • Modified carbohydrate polymers
  • Peptides
  • Synthetic DNA and oligonucleotides

If you’d like to learn more about our complex synthetics capabilities, please contact us – we enjoy solving challenges, and we’d love to hear more about yours.